Which ocular disease might involve bilateral asymmetric changes seen on ultrasound?

Retinopathy of prematurity (ROP) is a condition that primarily affects premature infants and involves the abnormal development of retinal blood vessels. On ultrasound examination, ROP can show bilateral asymmetric changes due to the variable progression and severity of the disease in each eye. This means that while both eyes may be affected, they do not always demonstrate identical patterns or levels of disease, leading to asymmetry in findings.

As the condition progresses, one eye may exhibit more advanced stages of ROP compared to the other, resulting in differences in the appearance of retinal structures when evaluated through ultrasound. This bilateral asymmetry is characteristic of ROP, making it a significant consideration during examinations.

Other conditions listed do not typically present with bilateral asymmetric changes on ultrasound. For example, retinal detachment usually manifests similarly in both eyes or presents a more uniform pattern, glaucoma is characterized mainly by increased intraocular pressure and changes in the optic nerve head that are typically symmetrical unless unilateral glaucoma exists, while conjunctivitis primarily affects the conjunctiva and does not usually produce changes detectable via ultrasound in an asymmetric manner. Thus, ROP is the condition most associated with the scenario described in the question.